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Toxicological Analysis of New Materials

Nanomaterials of organic and inorganic nature have been used for a variety of applications ranging from catalysis to gas storage, and from biosensors to drug delivery. With extensive previous reports showing materials with dimension nano have unique physicochemical properties that lead to increased biosystems’ reactivity, and with increasing concerns regarding adverse health effects upon such nanomaterial’s implementation, there is a growing interest to evaluate the toxicological profiles of nanomaterials and how their characteristics can be controlled to lead to effective risk assessment and mitigation prior to their implementation.

Affiliated Faculty

Recent Publications

  1. Rose, O., Dinu, C.Z., "Analysis and correlations of metal-organic frameworks applications and toxicity", Health and Environmental Safety of Nanomaterials , in press (2020).
  2. Stueckle, T., White, A., Wagner, A., Gupta, R., Rojanasakul, Y., Dinu, C.Z., "Impacts of Organomodified Nanoclays and their Incinerated Byproducts on Bronchial Cell Monolayer Integrity", Chemical Research in Toxicology (2019) 32, 12, 2445-2458.
  3. Wagner, A., Q. Liu, Rose, O., Eden, A., Vijay A., Rojanasakul, Y., Dinu, C.Z., "Toxicity Screening of Two Prevalent Metal Organic Frameworks for Therapeutic Use in Human Lung Epithelial Cells", International Journal of Nanomedicine (2019) 14: 7583–7591.
  4. Kiratipaiboon, C., Stueckle, T., Ghosh, R., Rojanasakul, L., Chen, Y., Dinu, C. Z., Rojanasakul, Y., "Acquisition of Cancer Stem Cell-like Properties in Human Small Airway Epithelial Cells after a Long-term Exposure to Carbon Nanomaterials", Environmental Science: Nano, (2019) 7(6): 2152-2170.
  5. Wagner, A., White, A., Tang, M.C., Agarwal, S., Stueckle, T.A., Rojanasakul, Y., Gupta, R., Dinu, C.Z., " Incineration of Nanoclay Composites Leads to Byproducts with Reduced Cellular Reactivity," Scientific Reports 8 10709, (2018).